Strange Musical Genius of Harry Partch

excerpted from Wikipedia's entry on Harry Partch:
Partch was born on June 24, 1901 in Oakland, California soon after his parents, both Presbyterian missionaries, fled the Boxer Rebellion in China. He spent his childhood in small, remote towns in Arizona and New Mexico, where he heard and sang songs in Mandarin, Spanish, and American Indian languages.
Partch was sterile, probably due to childhood mumps, and most of his loving relationships were with men.[1]

As a child, he learned to play the clarinet, harmonium, viola, piano, and guitar. He began to compose at an early age, using the equal-tempered chromatic scale, the tuning system most common in Western music. However, Partch grew frustrated with what he felt were imperfections of the standard system of musical tuning, believing that this system was unsuitable for reflecting the subtle melodic contours of dramatic speech, and as a result, he burned all of his early works.
Interested in the potential musicality of speech, Partch invented and constructed instruments that could underscore the intoning voice, and he developed musical notations that accurately and practically instructed players as to how to play the instruments. His first such instrument was the "Monophone," later known as the "Adapted viola."
Harry Partch's desire to use a different system of tuning inspired him to modify existing instruments and create new ones. He was, in his own words, "a philosophic music-man seduced into carpentry".
His adapted instruments include the Adapted Viola (a viola fitted with a cello neck which extends the range by a fourth, and has changeable bridges to allow triple-stops to be sustained) and three Adapted Guitars: a guitar with the equal tempered frets replaced by a complex system of justly tuned frets, a guitar tuned in octaves, or 2/1's, played by moving a pyrex rod along the strings, much like a slide guitar, and a 10-string fretless guitar played in a similar manner to his other fretless guitar, but with a wildly different tuning.
He re-tuned the reeds of several reed organs and labeled the keys with a color code. The first one was called the Ptolemy, in tribute to the ancient music theorist Claudius Ptolemaeus, whose musical scales included ratios of the 11-limit, as Partch's did. The others were called Chromelodeons, a portmanteau of chrome (meaning "color") and melodeon.

Partch is famous for his 43-tone scale, even though he used many different scales in his work and the number of divisions is theoretically infinite.
Partch created and maintained his own record label, "Gate 5", to release recordings of his works and generate income. Towards the end of his life, Columbia Records made recordings of some of his works, including Delusion of the Fury, which helped increase public attention to his work. He remains a somewhat obscure figure, but is well known to experimental musicians (especially those interested in microtonality) and instrument-builders, and he is considered by many to be one of the most significant composers of the 20th century.